Epstein-Barr virus (EBV)-associated B-cell post-transplantation lymphoproliferative\ndisorder (PTLD) is a severe complication following solid-organ\ntransplantation (SOT) and allogeneic hematopoietic stem cell transplantation\n(HSCT). We present a case of a 15-year-old male developing a monomorphic\nB-cell PTLD after receiving an allogenic stem cell transplant for acute acute\nmyeloid leukemia. A diagnostic lymph node biopsy revealed monomorphic\ntype, B cell phenotype, associated with Epstein-Barr virus, consistent with\npost-transplant lymphoproliferative disorder (PTLD). The morbidity and\nmortality of PTLD are high, and there is no standard protocol for treatment\nof PTLD. To prevent the occurrence of PTLD and early intervention are important\nfor the prognosis of patients.
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